JBJS | Platelet-Rich Plasma Differs According to Preparation Method and Human Variability

JBJS | Platelet-Rich Plasma Differs According to Preparation Method and Human Variability
The content and concentrations of platelets, white blood cells, and growth factors for each method of separation differed significantly. All separation techniques resulted in a significant increase in platelet concentration compared with native blood. Platelet and white blood-cell concentrations of the PRP_HP procedure were significantly higher than platelet and white blood-cell concentrations produced by the so-called single-step PRP_LP and the so-called two-step PRP_DS procedures, although significant differences between PRP_LP and PRP_DS were not observed. Comparing the results of the three blood draws with regard to the reliability of platelet number and cell counts, wide variations of intra-individual numbers were observed.